Researchers from the UCSF in the Journal of the American Medical Association concluded in a meta-analysis (here and here) of data from dozens of medical reports and studies that fetuses feel no pain until the third trimester of pregnancy. There is an emerging consensus among developmental neurobiologists that the establishment of thalamocortical connections (at about 26 weeks) is a critical event with regard to fetal perception of pain. Because pain can involve sensory, emotional and cognitive factors, it may be "impossible to know" when painful experiences are perceived, even if it is known when thalamocortical connections are established.
Electroencephalography suggests the capacity for functional pain perception in premature infants probably does not exist before 29 or 30 weeks; this study asserted that withdrawal reflexes and changes in heart rates and hormone levels in response to invasive procedures are reflexes that do not indicate fetal pain.
Also in 2005, Mellor and colleagues reviewed several lines of evidence that suggested a fetus does not awaken during its time in the womb. Mellor notes that much of the literature on fetal pain simply extrapolates from findings and research on premature babies. He questions the value of such data:
Systematic studies of fetal neurological function suggest, however, that there are major differences in the in utero environment and fetal neural state that make it likely that this assumption is substantially incorrect.
Mellor and his team detected the presence of such chemicals as adenosine, pregnanolo
ne, and prostaglan
din-D2 in both human and animal fetuses, indicating that
the fetus is both sedated and anesthetized in the womb.
These chemicals are oxidized with the newborn's first few breaths and washed out of the tissues, allowing consciousness to occur. If the fetus is asleep throughout gestation then the possibility of fetal pain is greatly minimized. “A fetus,” Mellor told the NYTimes, “is not a baby who just hasn’t been born yet.”Read the Article at HuffingtonPost
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